Enantioselective Dechlorination of Polychlorinated Biphenyls in Dehalococcoides mccartyi CG1.

ABSTRACT: Reductive dehalogenation mediated by organohalide-respiring bacteria plays a critical role in the global cycling of organohalides. Nonetheless, information on the dehalogenation enantioselectivity of organohalide-respiring bacteria remains limited. In this study, we report the enantioselective dechlorination of chiral polychlorinated biphenyls (PCBs) by Dehalococcoides mccartyi CG1. CG1 preferentially removed halogens from the (-)-enantiomers of the three major environmentally relevant chiral PCBs (PCB174, PCB149, and PCB132), and the enantiomer compositions of the dechlorination products depended on their parent organohalides. The in vitro assays with crude cell extracts or concentrated whole cells and the in vivo experiments with living cells showed similar enantiose

SUBMITTER: Yu L 

PROVIDER: S-EPMC6193387 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature