Associations of preoperative breast magnetic resonance imaging with subsequent mastectomy and breast cancer mortality.

ABSTRACT:

Purpose

To examine associations between pre-operative magnetic resonance imaging (MRI) use and clinical outcomes among women undergoing breast-conserving surgery (BCS) with or without radiotherapy for early-stage breast cancer.

Methods

We identified women from the Surveillance, Epidemiology, and End Results-Medicare dataset aged 67-94 diagnosed during 2004-2010 with stage I/II breast cancer who received BCS. We compared subsequent mastectomy and breast cancer mortality with versus without pre-operative MRI, using Cox regression and competing risks models. We further stratified by receipt of radiotherapy for subgroup analyses.

Results

Our sample consisted of 24,379 beneficiaries, 4691 (19.2%) of whom received pre-operative MRI. Adjusted rates of subsequent mastectomy a

SUBMITTER: Wang SY 

PROVIDER: S-EPMC6193824 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature