The Cell Activation Phenomena in the Cold Atmospheric Plasma Cancer Treatment.

ABSTRACT: Cold Atmospheric Plasma (CAP) is an ionized gas with a near room temperature. CAP is a controllable source for reactive species, neutral particles, electromagnetic field and UV radiation. CAP showed the promising application in cancer treatment through the demonstration in vitro and in vivo. In this study, we first demonstrate the existence of an activation state on the CAP-treated cancer cells, which drastically decreases the threshold of cell vulnerability to the cytotoxicity of the CAP-originated reactive species such as H₂O₂ and NO₂^-. The cytotoxicity of CAP treatment is still dependent on the CAP-originated reactive species. The activation state of cancer cells will not cause noticeable cytotoxicity. This activation is an instantaneous proce

SUBMITTER: Yan D 

PROVIDER: S-EPMC6194007 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature