Effects of cyclic changes in population size on neutral genetic diversity.

ABSTRACT: Recurrent changes in population size are often observed in nature, influencing the efficiency of selection and consequently affecting organismal evolution. Thus, it is important to know whether such changes occurred in the past history of a focal population of evolutionary interests. Here, we focused on cyclic changes in population size and investigated the distributional properties of Tajima's D and its power to distinguish a cyclic change model compared with the standard neutral model, changing the frequency and magnitude of the cyclic change. With very low or very high frequencies of the cycle, the distribution of Tajima's D was similar to that in a constant size population, as demonstrated by previous theoretical works. Otherwise, its mean was negative or positive, and it

SUBMITTER: Nakamura H 

PROVIDER: S-EPMC6194295 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature