Smoking as a risk factor for lung cancer in women and men: a systematic review and meta-analysis.

ABSTRACT:

Objectives

To investigate the sex-specific association between smoking and lung cancer.

Design

Systematic review and meta-analysis.

Data sources

We searched PubMed and EMBASE from 1 January 1999 to 15 April 2016 for cohort studies. Cohort studies before 1 January 1999 were retrieved from a previous meta-analysis. Individual participant data from three sources were also available to supplement analyses of published literature.

Eligibility criteria for selecting studies

Cohort studies reporting the sex-specific relative risk (RR) of lung cancer associated with smoking.

Results

Data from 29 studies representing 99 cohort studies, 7 million individuals and >50 000 incident lung cancer cases were included. The sex-specific RRs and their ratio comparing women

SUBMITTER: O'Keeffe LM 

PROVIDER: S-EPMC6194454 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature