Gestational Weight Gain in Women With Polycystic Ovary Syndrome: A Controlled Study.

ABSTRACT:

Context

Women with polycystic ovary syndrome (PCOS) have increased risk for pregnancy complications, possibly related to pre-existing obesity and excessive gestational weight gain (GWG).

Objectives

To assess the contributions of diagnosis and preconception weight on GWG and perinatal outcomes.

Research design and methods

Prospective cohort study of singleton pregnancies in PCOS (n = 164) and ovulatory controls (n = 176) from infertility treatment.

Main outcome measures

GWG, birthweight, pregnancy complications.

Results

From preconception baseline, normal-weight women with PCOS gained 2.3 pounds more during the first trimester (95% CI, 0.3 to 4.3; P = 0.02), and by the end of the second trimester, 4.2 pounds more than controls (95% CI, 0.7 to 7.7; P = 0.0

SUBMITTER: Kent J 

PROVIDER: S-EPMC6194806 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature