Evaluation of Linguistic Markers of Word-Finding Difficulty and Cognition in Parkinson's Disease.

ABSTRACT:

Purpose

Early cognitive symptoms such as word-finding difficulty (WFD) in daily conversation are common in Parkinson's disease (PD), but studies have been limited by a lack of feasible, quantitative measures. Linguistic analysis, focused on pauses in speech, may yield markers of impairment of cognition and communication in PD. The objective of this study was to evaluate the relationship of linguistic markers in semistructured speech to WFD symptoms and cognitive function in PD.

Method

Speech recordings of description of the Cookie Theft picture in 53 patients with PD without dementia and 23 elderly controls were analyzed with Praat software. Montreal Cognitive Assessment (MoCA; Nasreddine et al., 2005), category naming fluency, and confrontation naming tests were administere

SUBMITTER: Smith KM 

PROVIDER: S-EPMC6195062 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature