Prognostic factors determining poor postsurgical outcomes of mesial temporal lobe epilepsy.

ABSTRACT:

Objectives

To investigate the long-term postoperative outcomes and predictive factors associated with poor surgical outcomes in mesial temporal lobe epilepsy (MTLE).

Materials and methods

We enrolled patients with MTLE who underwent resective surgery at single university-affiliated hospital. Surgical outcomes were determined using a modified Engel classification at the 2nd and 5th years after surgery and the last time of follow-up.

Results

The mean duration of follow-up after surgery was 7.6 ± 3.7 years (range, 5.0-21.0 years). 334 of 400 patients (83.5%) were seizure-free at the 5th postoperative year. Significant predictive factors of a poor outcome at the 5th year were a history of generalized tonic clonic (GTC) seizures (odds ratio, OR; 2.318), bi-temporal interic

SUBMITTER: Shin JH 

PROVIDER: S-EPMC6195284 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature