Tooth loss as a risk factor for dementia: systematic review and meta-analysis of 21 observational studies.

ABSTRACT:

Background

Tooth loss is suggested to be associated with an increased risk of dementia in many studies. But the relationship between tooth loss and dementia is not yet fully understood. This systematic review and meta-analysis aimed to determine the relative effect of tooth loss on dementia risk.

Methods

An electronic search of PubMed, Scopus, Embase, and Web of Knowledge was conducted in March 2018 to identify relevant observational studies with the English language restriction. Studies were included if they assessed the relationship between tooth loss and risk of dementia. Study quality was detected by the modified Downs and Black scale. Odds risks (ORs) were pooled using a random-effects model in the crude model.

Results

The literature search initially yielded 1574

SUBMITTER: Fang WL 

PROVIDER: S-EPMC6195976 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature