Neutrophil/lymphocyte ratio is helpful for predicting weaning failure: a prospective, observational cohort study.

ABSTRACT:

Background

To assess the usefulness of the neutrophil/lymphocyte ratio (NLR), a marker of inflammation and/or stress, for predicting weaning failure in patients receiving invasive mechanical ventilation (IMV), compared to levels of leukocytes and C-reactive protein (CRP).

Methods

This observational prospective cohort study was conducted from July 2013 to December 2016 in an intensive care unit in China, enrolling 269 consecutive patients receiving IMV. Patients underwent a spontaneous breathing trial (SBT) if they were ready to wean, and underwent extubation if they passed the SBT. The evaluated markers were measured immediately prior to SBT, and compared between weaning-failure and weaning-success patients. Receiver-operating characteristic (ROC) curve and logistic regressi

SUBMITTER: Luo Z 

PROVIDER: S-EPMC6196202 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature