Validation of a Questionnaire for Distinguishing X-Linked Dystonia Parkinsonism From Its Mimics.

ABSTRACT: Objectives: X-linked dystonia parkinsonism (XDP) is a neurodegenerative movement disorder endemic to the island of Panay in the Philippines. We undertook a population-based prevalence study to enumerate all cases of XDP in Panay. We first developed a 4-item questionnaire to distinguish XDP suspects from the general population. In the present study we aimed to revalidate this questionnaire to distinguish XDP from similar conditions so as to give it greater utility in the clinical setting. Patients and Methods: A total of 306 subjects (114 cases and 192 controls) were screened in from the 16 towns and 1 city of Capiz province. Their responses to the previously developed 4-item questionnaire were collected and multivariable logistic regression was performed to develop a predicti

SUBMITTER: Diestro JDB 

PROVIDER: S-EPMC6196251 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature