Oscillatory fluid flow drives scaling of contraction wave with system size.

ABSTRACT: Flows over remarkably long distances are crucial to the functioning of many organisms, across all kingdoms of life. Coordinated flows are fundamental to power deformations, required for migration or development, or to spread resources and signals. A ubiquitous mechanism to generate flows, particularly prominent in animals and amoebas, is actomyosin cortex-driven mechanical deformations that pump the fluid enclosed by the cortex. However, it is unclear how cortex dynamics can self-organize to give rise to coordinated flows across the largely varying scales of biological systems. Here, we develop a mechanochemical model of actomyosin cortex mechanics coupled to a contraction-triggering, soluble chemical. The chemical itself is advected with the flows generated by the cortex-driven deformatio

SUBMITTER: Julien JD 

PROVIDER: S-EPMC6196541 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature