Incidence and impact on outcomes of acute kidney injury after a stroke: a systematic review and meta-analysis.

ABSTRACT:

Background

Patients with chronic kidney disease have worse outcomes after stroke. However, the burden of acute kidney injury after stroke has not been extensively investigated.

Methods

We used MEDLINE and Embase to conduct a systematic review and meta-analysis of published studies that provided data on the risk of AKI and outcomes in adults after ischemic and hemorrhagic stroke. Pooled incidence was examined using the Stuart-Ord method in a DerSimonian-Laird model. Pooled Odds Ratios and 95% confidence intervals were calculated for outcomes using a random effects model. This review was registered with PROSPERO (CRD42017064588).

Results

Eight studies were included, five from the United States, representing 99.9% of included patients. Three studies used established acut

SUBMITTER: Arnold J 

PROVIDER: S-EPMC6196566 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature