Smartphone-based pathogen diagnosis in urinary sepsis patients.

ABSTRACT:

Background

There is an urgent need for rapid, sensitive, and affordable diagnostics for microbial infections at the point-of-care. Although a number of innovative systems have been reported that transform mobile phones into potential diagnostic tools, the translational challenge to clinical diagnostics remains a significant hurdle to overcome.

Methods

A smartphone-based real-time loop-mediated isothermal amplification (smaRT-LAMP) system was developed for pathogen ID in urinary sepsis patients. The free, custom-built mobile phone app allows the phone to serve as a stand-alone device for quantitative diagnostics, allowing the determination of genome copy-number of bacterial pathogens in real time.

Findings

A head-to-head comparative bacterial analysis of urine from sep

SUBMITTER: Barnes L 

PROVIDER: S-EPMC6197494 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature