Preoperative anemia and perioperative blood transfusion in head and neck squamous cell carcinoma.

ABSTRACT:

Objectives

To evaluate the impact of preoperative anemia and perioperative blood transfusion (PBT) on disease free (DFS) and overall survival (OS) of patients with head and neck squamous cell carcinoma (HNSCC).

Methods

Retrospective study of 354 patients primarily treated with surgery between 2006 and 2016. Cases were selected according to completeness and accuracy of available clinical data. Thus, a selection bias cannot be excluded. Patients who received PBT were identified by our controlling department and verified by our blood bank data base.

Results

Both, preoperative anemia and PBT significantly decreased OS in univariate analysis. Although PBT was needed more frequently by older patients in worse physical conditions with more advanced HNSCC, subgroup analysis a

SUBMITTER: Baumeister P 

PROVIDER: S-EPMC6197687 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature