A novel inflammation-based nomogram system to predict survival of patients with hepatocellular carcinoma.

ABSTRACT:

Background and aim

The existed staging systems were limited in the accuracy of prediction for overall survival (OS) of hepatocellular carcinoma (HCC) patients. The aim of this study is to establish a novel inflammation-based prognostic system with nomogram for HCC patients.

Methods

A prospective cohort of patients was recruited and assigned to the training cohort (n = 659) and validation cohort (n = 320) randomly. Different inflammation-based score systems were evaluated to select the best one predicting overall survival (OS). The inflammation-based score system with the highest predicting value and the parameters best reflecting tumor burden identified by multivariate analysis were selected to construct a novel predicting nomogram system. The predictive accuracy and discrim

SUBMITTER: Chen J 

PROVIDER: S-EPMC6198220 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature