Risk-based breast cancer follow-up stratified by age.

ABSTRACT: Although personalization of cancer care is recommended, current follow-up after the curative treatment of breast cancer is consensus-based and not differentiated for base-line risk. Every patient receives annual follow-up for 5 years without taking into account the individual risk of recurrence. The aim of this study was to introduce personalized follow-up schemes by stratifying for age. Using data from the Netherlands Cancer Registry of 37 230 patients with early breast cancer between 2003 and 2006, the risk of recurrence was determined for four age groups (<50, 50-59, 60-69, >70). Follow-up was modeled with a discrete-time partially observable Markov decision process. The decision to test for recurrences was made two times per year. Recurrences could be detected by mammography as well as

SUBMITTER: Witteveen A 

PROVIDER: S-EPMC6198239 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature