Evaluation of markers of outcome in real-world treatment of diabetic macular edema.

ABSTRACT:

Objective

To evaluate short-term markers of outcome in diabetic macular edema (DME).

Methods

Prospective interventional case series included 122 eyes of 122 patients with recently diagnosed DME. Eyes were treated with a 3-monthly loading dose of ranibizumab or aflibercept and pro re nata thereafter. Serial enhanced deep imaging SD-OCT high resolution scans were used to measure subfoveal choroidal thickness (SFCT) and central retinal thickness (CRT). Anatomic (10% CRT decrease) and functional responses (best corrected visual acuity, BCVA gain ≥5 letters) were assessed at 3 months and 6 months using univariate and multivariate analyses. Parameters tested were gender, duration of diabetes, HbA1c, hypertension, CRT, SFCT, BCVA, ellipsoid zone (EZ) status, subfoveal neuroretinal

SUBMITTER: Campos A 

PROVIDER: S-EPMC6198537 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature