Decision Criteria for Large Vessel Occlusion Using Transcranial Doppler Waveform Morphology.

ABSTRACT: Background: The current lack of effective tools for prehospital identification of Large Vessel Occlusion (LVO) represents a significant barrier to efficient triage of stroke patients and detriment to treatment efficacy. The validation of objective Transcranial Doppler (TCD) metrics for LVO detection could provide first responders with requisite tools for informing stroke transfer decisions, dramatically improving patient care. Objective: To compare the diagnostic efficacy of two such candidate metrics: Velocity Asymmetry Index (VAI), which quantifies disparity of blood flow velocity across the cerebral hemispheres, and Velocity Curvature Index (VCI), a recently proposed TCD morphological biomarker. Additionally, we investigate a simple decision tree combining both metrics.

SUBMITTER: Thorpe SG 

PROVIDER: S-EPMC6199366 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature