Secondary metabolite production and the safety of industrially important members of the Bacillus subtilis group.

ABSTRACT: Members of the 'Bacillus subtilis group' include some of the most commercially important bacteria, used for the production of a wide range of industrial enzymes and fine biochemicals. Increasingly, group members have been developed for use as animal feed enhancers and antifungal biocontrol agents. The group has long been recognised to produce a range of secondary metabolites and, despite their long history of safe usage, this has resulted in an increased focus on their safety. Traditional methods used to detect the production of secondary metabolites and other potentially harmful compounds have relied on phenotypic tests. Such approaches are time consuming and, in some cases, lack specificity. Nowadays, accessibility to genome data and associated bioinformatical tools provides a powerful m

SUBMITTER: Harwood CR 

PROVIDER: S-EPMC6199538 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature