Efficacy and effectiveness of Ceftaroline Fosamil in patients with pneumonia: a systematic review and meta-analysis.

ABSTRACT:

Background

Pneumonia is a relevant clinical and public health issue worldwide frequently associated with infections caused by Multi-Drug Resistant (MDR) pathogens. Ceftaroline fosamil is a promising new antibiotics with broad-spectrum bacterial activity. The aim of this systematic review and meta-analysis is to assess the efficacy and the effectiveness of ceftaroline fosamil in community-acquired (CAP), hospital-acquired (HAP), healthcare-associated (HCAP) and ventilator-associated (VAP) pneumonia.

Methods

A systematic review and meta-analysis was carried out retrieving both experimental and observational studies.

Results

A total of 2364 records was found and 14 manuscripts were finally considered eligible. The pooled efficacy/effectiveness was 81.2% (I²: 1

SUBMITTER: Sotgiu G 

PROVIDER: S-EPMC6199731 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature