The impact of intraoperative goal-directed fluid therapy on complications after pancreaticoduodenectomy.

ABSTRACT:

Introduction

Optimal fluid balance is critical to minimize anastomotic edema in patients undergoing pancreaticoduodenectomy. We examined the effects of decreased fluid administration on rates of postoperative pancreatic leak and delayed gastric emptying.

Methods

Retrospective study of 105 patients undergoing pancreaticoduodenectomy at a single institution from January 2015 through July 2016. Stroke volume variation (SVV) was tracked and titrated during the procedure. A comparative analysis of postoperative complications was performed between patients with a median SVV < 12 during the extirpative and reconstructive phases of the procedure compared with patients with an SVV ≥ 12.

Results

Of 64 patients who met selection criteria, 42 (65.6%) had a SVV < 12 and 22 (34.4%)

SUBMITTER: Sulzer JK 

PROVIDER: S-EPMC6199772 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature