Protocol for a phase III RCT and economic analysis of two exercise delivery methods in men with PC on ADT.

ABSTRACT:

Background

Androgen deprivation therapy (ADT) is commonly used to treat prostate cancer. However, side effects of ADT often lead to reduced quality of life and physical function. Existing evidence demonstrates that exercise can ameliorate multiple treatment-related side effects for men on ADT, yet adherence rates are often low. The method of exercise delivery (e.g., supervised group in-centre vs. individual home-based) may be important from clinical and economic perspectives; however, few studies have compared different delivery models. Additionally, long-term exercise adherence and an understanding of predictors of adherence are critical to achieving sustained benefits, but such data are lacking. The primary aim of this multi-centre phase III non-inferiority randomized controlled

SUBMITTER: Alibhai SMH 

PROVIDER: S-EPMC6199786 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature