Roles and functions of Atp6ap2 in the brain.

ABSTRACT: The classical renin-angiotensin system (RAS) in the body has been studied intensively in the last decades, since it is known that this system is involved in the regulation of blood pressure. Since nearly all members of the classical RAS have also been identified within the brain in the last decades and due to the existence of the blood-brain barrier, a RAS within the brain (bRAS) that is largely independent from the peripheral RAS has been postulated. All members of the angiotensin family as e.g., angiotensin II, angiotensin IV and angiotensin II (1-7) along with the respective receptors (e.g., angiotensin II receptor type 1 (AT1), angiotensin II receptor type 2 (AT2), angiotensin IV receptor (AT4), angiotensin II (1-7) receptor (Mas)) have been identified within the brain. Moreover, a rec

SUBMITTER: Bracke A 

PROVIDER: S-EPMC6199949 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature