The Roles of Two hfq Genes in the Virulence and Stress Resistance of Burkholderia glumae.

ABSTRACT: The Hfq protein is a global small RNA chaperone that interacts with regulatory bacterial small RNAs (sRNA) and plays a role in the post-transcriptional regulation of gene expression. The roles of Hfq in the virulence and pathogenicity of several infectious bacteria have been reported. This study was conducted to elucidate the functions of two hfq genes in Burkholderia glumae, a causal agent of rice grain rot. Therefore, mutant strains of the rice-pathogenic B. glumae BGR1, targeting each of the two hfq genes, as well as the double defective mutant were constructed and tested for several phenotypic characteristics. Bacterial swarming motility, toxoflavin production, virulence in rice, siderophore production, sensitivity to H₂O₂, and lipase p

SUBMITTER: Kim J 

PROVIDER: S-EPMC6200039 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature