Patients with chronic mesenteric ischemia have an altered sublingual microcirculation.

ABSTRACT:

Background

Little is known about the microcirculatory alterations in patients with chronic mesenteric ischemia (CMI). We hypothesized that patients with CMI have an impaired microcirculatory function and show an oral microcirculatory response after caloric challenge compared to healthy controls.

Methods

All patients and controls received the standard workup for CMI. Sublingual micro-circulation was evaluated before (T0) and 20 minutes after (T1) feeding. The total vessel density (TVD; mm/mm²), perfused vessel density (PVD; mm/mm²), proportion of perfused vessels (PPV; %) and microvascular flow index (MFI; AU) were assessed.

Results

We included 12 patients (63.2 years [IQR 48.8-70.4 years], 67% males) and 12 controls (32.7 years [IQR 27.7-38.1 yea

SUBMITTER: Harki J 

PROVIDER: S-EPMC6200368 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature