Injury Characteristics and von Willebrand Factor for the Prediction of Acute Respiratory Distress Syndrome in Patients With Burn Injury: Development and Internal Validation.

ABSTRACT:

Objective

To derive and validate a prediction model for the development of ARDS in burn-injured patients.

Summary background data

Burn injury carries the highest incidence of acute respiratory distress syndrome (ARDS) among all predisposing conditions, but few studies exist on risk factors in these patients. Studies employing biomarkers and clinical risk factors for predicting ARDS mortality have recently been examined but none exist for onset of ARDS nor in patients with burn injury.

Methods

This was a prospective multicenter study of 113 patients with isolated burn injury or inhalation injury. Clinical variables and plasma biomarkers representative of endothelial injury, epithelial injury, or inflammation were collected within 24 hours of admission. The most parsimo

SUBMITTER: Afshar M 

PROVIDER: S-EPMC6200654 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature