Readily Functionalizable and Stabilizable Polymeric Particles with Controlled Size and Morphology by Electrospray.

ABSTRACT: Electrospraying is an effective and facile technique for the production of micro- or nanoparticles with tailored sizes, shapes, morphologies, and microstructures. We synthesized functionalizable poly(styrene-random-glycidyl methacrylate) copolymers and used them to fabricate microparticles via the electrospray technique. The sizes and morphologies of the electrosprayed particles are controlled by altering the process parameters (feed rate and applied voltage), and the composition and thermodynamic properties of the polymer (i.e., compatibility of the polymer with the solvent). We further investigated modifying the surfaces of the electrosprayed particles with 3-mercaptopropionic acid by a simple and efficient thiol-epoxy "click" reaction as a proof-of-concept demonstration that desired fun

SUBMITTER: Lee H 

PROVIDER: S-EPMC6200772 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature