Cognitive effects of stereotactic radiosurgery in adult patients with brain metastases: A systematic review.

ABSTRACT:

Purpose

Stereotactic radiation surgery (SRS) is increasingly applied in patients with brain metastases (BM) and is expected to have fewer adverse effects on cognitive functioning than whole brain radiation therapy (WBRT). Patients with BM are often confronted with a relatively short life expectancy, and the prevention or delay of cognitive decline to maintain quality of life is a clinically and highly relevant treatment goal. This review systematically and specifically evaluates the current literature on the cognitive effects of SRS in patients with BM.

Methods and materials

Published trials on SRS alone or in combination with WBRT, including objective assessment of cognitive functioning, were identified through a systematic search of the PubMed database up to March 2018.

SUBMITTER: Schimmel WCM 

PROVIDER: S-EPMC6200877 | biostudies-literature | 2018 Oct-Dec

REPOSITORIES: biostudies-literature