Improving prediction of surgical resectability over current staging guidelines in patients with pancreatic cancer who receive stereotactic body radiation therapy.

ABSTRACT:

Purpose

For patients with localized pancreatic cancer (PC) with vascular involvement, prediction of resectability is critical to define optimal treatment. However, the current definitions of borderline resectable (BR) and locally advanced (LA) disease leave considerable heterogeneity in outcomes within these classifications. Moreover, factors beyond vascular involvement likely affect the ability to undergo resection. Herein, we share our experience developing a model that incorporates detailed radiologic, patient, and treatment factors to predict surgical resectability in patients with BR and LA PC who undergo stereotactic body radiation therapy (SBRT).

Methods and materials

Patients with BR or LA PC who were treated with SBRT between 2010 and 2016 were included. The primary

SUBMITTER: Cheng Z 

PROVIDER: S-EPMC6200892 | biostudies-literature | 2018 Oct-Dec

REPOSITORIES: biostudies-literature