Association between whole grain intake and breast cancer risk: a systematic review and meta-analysis of observational studies.

ABSTRACT:

Background

Epidemiological studies have found that high whole grain intake may be associated with a reduced risk of breast cancer. However, the evidence has not been consistent. We conducted a meta-analysis to quantitatively assess the association between whole grain intake and breast cancer risk.

Methods

Relevant observational studies were identified by searching PubMed, Embase, Cochrane library databases, and Google Scholar through April 2017. Summary relative risk (RR) estimates were calculated using random-effects meta-analysis.

Results

A total of 11 studies, including 4 cohort and 7 case-control studies and involving 131,151 participants and 11,589 breast cancer cases, were included in the current meta-analysis. The pooled RR of breast cancer for those with high

SUBMITTER: Xiao Y 

PROVIDER: S-EPMC6201708 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature