Desulfurization-bromination: direct chain-end modification of RAFT polymers.

ABSTRACT: We report a simple and efficient transformation of thiol and thiocarbonylthio functional groups to bromides using stable and commercially available brominating reagents. This procedure allows for the quantitative conversion of a range of small molecule thiols (including primary, secondary and tertiary) to the corresponding bromides under mild conditions, as well as the facile chain-end modification of polystyrene (PS) homopolymers and block copolymers prepared by reversible addition-fragmentation chain transfer (RAFT) polymerization. Specifically, the direct chain-end bromination of PS prepared by RAFT was achieved, where the introduced terminal bromide remained active for subsequent modification or chain-extension using classical atom transfer radical polymerization (ATRP). This transform

SUBMITTER: Lee IH 

PROVIDER: S-EPMC6201749 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature