Do people with Alzheimer's disease improve with repeated testing? Unpacking the role of content and context in retest effects.

ABSTRACT:

Objective

retest effects may be attributed to 'repeated content' in neuropsychological tests such as words in word list-learning tests, or the 'testing context' which involves procedural memory and reduced test anxiety following repeated administration. Alzheimer's Disease (AD) severely impairs episodic memory, so longitudinal cognitive testing among people with dementia may reveal the relative contributions of content versus context to retest effects in neuropsychological testing.

Method

we used data from the Critical Path Institute's repository of placebo arm data from randomized controlled trials (RCTs) of dementia conducted by participating pharmaceutical companies (N = 990 people, 4,170 study visits, up to 2.4 years of follow-up). To estimate retest effects on the Mini-

SUBMITTER: Gross AL 

PROVIDER: S-EPMC6201832 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature