Association of Blood Pressure Measurements With Peripheral Artery Disease Events.

ABSTRACT:

Background

Current guidelines recommend treating hypertension in patients with peripheral artery disease (PAD) to reduce the risk of cardiac events and stroke, but the effect of reducing blood pressure on lower extremity PAD events is largely unknown. We investigated the association of blood pressure with lower extremity PAD events using data from the ALLHAT trial (Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial).

Methods

ALLHAT investigated the effect of different antihypertensive medication classes (chlorthalidone, amlodipine, lisinopril, or doxazosin) on cardiovascular events. With the use of these data, the primary outcome in our analysis was time to first lower extremity PAD event, defined as PAD-related hospitalization, procedures, medical t

SUBMITTER: Itoga NK 

PROVIDER: S-EPMC6202170 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature