Improvement of caproic acid production in a Clostridium kluyveri H068 and Methanogen 166 co-culture fermentation system.

ABSTRACT: The aim of this study was to develop a bioprocess capable of producing caproic acid using a binary fermentation system consisting of Clostridium kluyveri H068 and Methanogen 166 which could then be applied to the brewing of Chinese strong flavor liquor. We initially explored the mechanism by which the Methanogen 166 strain facilitates caproic acid accumulation, revealing its ability to convert accumulated H₂ that is produced by C. kluyveri H068 into methane, thereby eliminating the hydrogen-mediated feedback inhibition that normally constrains C. kluyveri H068 and thus enhancing caproic acid production. In addition, laboratory experiments were conducted to optimize this binary fermentation system, allowing us to determine that the optimum conditions for caproic acid production a

SUBMITTER: Yan S 

PROVIDER: S-EPMC6202304 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature