EzColocalization: An ImageJ plugin for visualizing and measuring colocalization in cells and organisms.

ABSTRACT: Insight into the function and regulation of biological molecules can often be obtained by determining which cell structures and other molecules they localize with (i.e. colocalization). Here we describe an open source plugin for ImageJ called EzColocalization to visualize and measure colocalization in microscopy images. EzColocalization is designed to be easy to use and customize for researchers with minimal experience in quantitative microscopy and computer programming. Features of EzColocalization include: (i) tools to select individual cells and organisms from images; (ii) filters to select specific types of cells and organisms based on physical parameters and signal intensity; (iii) heat maps and scatterplots to visualize the localization patterns of reporters; (iv) multiple metrics to

SUBMITTER: Stauffer W 

PROVIDER: S-EPMC6202351 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature