Constitutive hyperproduction of sorbicillinoids in Trichoderma reesei ZC121.

ABSTRACT:

Background

In addition to its outstanding cellulase production ability, Trichoderma reesei produces a wide variety of valuable secondary metabolites, the production of which has not received much attention to date. Among them, sorbicillinoids, a large group of hexaketide secondary metabolites derived from polyketides, are drawing a growing interest from researchers because they exhibit a variety of important biological functions, including anticancer, antioxidant, antiviral, and antimicrobial properties. The development of fungi strains with constitutive, hyperproduction of sorbicillinoids is thus desired for future industry application but is not well-studied. Moreover, although T. reesei has been demonstrated to produce sorbicillinoids with the corresponding gene cl

SUBMITTER: Li C 

PROVIDER: S-EPMC6202828 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature