Whole genome sequencing, variant analysis, phylogenetics, and deep sequencing of Zika virus strains.

ABSTRACT: The recent emergence of Zika virus (ZIKV) has been concentrated in the Caribbean, Southeastern United States, and South- and Central America; resulting in travel-based cases being reported around the globe. As multi-disciplinary collaborations are combatting the ZIKV outbreak, the need to validate the sequence of existing strains has become apparent. Here, we report high-quality sequence data for multiple ZIKV strains made publicly available through the National Institutes of Health- (NIH) funded biorepository, BEI Resources (www.beiresources.org). Next-generation sequencing, 3' rapid amplification of cDNA ends (RACE), and viral genome annotation pipelines generated GenBank sequence records for 16 BEI Resources strains. Minor variants, consensus mutations, and consensus insertions/deletion

SUBMITTER: Shrivastava S 

PROVIDER: S-EPMC6203802 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature