Waist circumference and risk of 23 site-specific cancers: a population-based cohort study of Korean adults.

ABSTRACT:

Background

Large waist circumference (WC) is a risk factor for several site-specific cancers, but a large-scale systematic investigation across all common cancers adjusted for potential confounders has not been conducted. This study aimed to evaluate the possible links between WC and common cancers.

Methods

We prospectively examined the association between WC and the risk of cancers in a 7-year cohort study of nearly 22.9 million Korean adults. Using the claims database merged with the national health check-up data, we fitted proportional hazard models to investigate associations between WC and 23 of the most common cancers, with adjustment for potential confounders, including body mass index (BMI). We also evaluated the modification of BMI on the relationships between WC an

SUBMITTER: Lee KR 

PROVIDER: S-EPMC6203821 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature