Long-term outcomes of the 2-week schedule of hypofractionated radiotherapy for recurrent hepatocellular carcinoma.

ABSTRACT:

Background

The 2-week schedule of hypofractionated radiotherapy as a salvage treatment for hepatocellular carcinoma (HCC) has previously exhibited promising results; this study aimed to assess its long-term clinical outcomes in patients with recurrent HCC ineligible for curative treatments.

Methods

We retrospectively enrolled 77 patients (84 lesions) with HCC who were treated with hypofractionated radiotherapy between December 2008 and July 2013. Primary inclusion criteria were HCC unsuitable for curative treatments and HCC located within 2 cm of a critical normal organ. We administered 3.5-5 Gy/fraction for 2 weeks, resulting in a total dose of 35-50 Gy.

Results

The median follow-up period was 33.6 (range, 4.8-78.3) months. The 3- and 5-year overall survival rates we

SUBMITTER: Park J 

PROVIDER: S-EPMC6203968 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature