Factors associated with recurrence and mortality in central line-associated bloodstream infections: a retrospective cohort study.

ABSTRACT:

Background

Central line-associated bloodstream infections (CLABSIs) are associated with increased mortality, hospital length of stay, and cost. Antimicrobial treatment guidelines for CLABSIs are primarily based on expert opinion. We hypothesized that shorter antimicrobial treatment duration is associated with decreased 60-day recurrence-free survival.

Methods

A retrospective cohort study of all adults with hospital-acquired CLABSIs (HA-CLABSIs) over 5 years at a single tertiary care academic hospital was performed. The time from the end of effective antimicrobial treatment until recurrence of infection or mortality, censored at 60 days after the end of antimicrobial treatment, represented the primary outcome. Effective antimicrobial treatment was defined as the administratio

SUBMITTER: Huerta LE 

PROVIDER: S-EPMC6204025 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature