Ontology highlight
ABSTRACT:
SUBMITTER: Tufford AR
PROVIDER: S-EPMC6204233 | biostudies-literature | 2018 May
REPOSITORIES: biostudies-literature
Cell reports 20180501 8
Newborn neurons follow molecular cues to reach their final destination, but whether early life experience influences lamination remains largely unexplored. As light is among the first stimuli to reach the developing nervous system via intrinsically photosensitive retinal ganglion cells (ipRGCs), we asked whether ipRGCs could affect lamination in the developing mouse retina. We show here that ablation of ipRGCs causes cone photoreceptors to mislocalize at different apicobasal positions in the ret ...[more]