The intensive care medicine research agenda on multidrug-resistant bacteria, antibiotics, and stewardship.

ABSTRACT:

Purpose

To concisely describe the current standards of care, major recent advances, common beliefs that have been contradicted by recent trials, areas of uncertainty, and clinical studies that need to be performed over the next decade and their expected outcomes with regard to the management of multidrug-resistant (MDR) bacteria, antibiotic use, and antimicrobial stewardship in the intensive care unit (ICU) setting.

Methods

Narrative review based on a systematic analysis of the medical literature, national and international guidelines, and expert opinion.

Results

The prevalence of infection of critically ill patients by MDR bacteria is rapidly evolving. Clinical studies aimed at improving understanding of the changing patterns of these infections in ICUs are urgently

SUBMITTER: Kollef MH 

PROVIDER: S-EPMC6204331 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature