Inhibitory effect of microalgae and cyanobacteria extracts on influenza virus replication and neuraminidase activity.

ABSTRACT:

Background

The influenza virus can cause seasonal infections with mild to severe symptoms, circulating worldwide, and it can affect people in any age group. Therefore, this infection is a serious public health problem that causes severe illness and death in high-risk populations. Every year, 0.5% of the world's population is infected by this pathogen. This percentage can increase up to ten times during pandemics. Influenza vaccination is the most effective way to prevent disease. In addition, anti-influenza drugs are essential for prophylactic and therapeutic interventions. The oseltamivir (OST, a neuraminidase inhibitor) is the primary antiviral used in clinics during outbreaks. However, OST resistant viruses may emerge naturally or due to antiviral pressure, with a prevalence of

SUBMITTER: Silva T 

PROVIDER: S-EPMC6204821 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature