Online study partner-reported cognitive decline in the Brain Health Registry.

ABSTRACT:

Introduction

Methods for efficiently identifying cognitive decline and Alzheimer's disease (AD) are a critical unmet need. The goal of this work was to validate novel online study partner (SP)-reported outcomes to identify cognitive decline in older adults.

Methods

In older adults enrolled in the Brain Health Registry, we analyzed associations between SP-reported cognitive decline, measured by the Everyday Cognition Scale, and either (1) participant cognition, assessed by Cogstate Brief Battery or (2) participant-reported diagnosis of mild cognitive impairment or AD.

Results

We found strong associations between SP-reported Everyday Cognition Scale and both Cogstate scores and participant diagnosis. The associations were cognitive domain specific, dependant on particip

SUBMITTER: Nosheny RL 

PROVIDER: S-EPMC6205111 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature