A randomized controlled trial of combined executive function and memory training on the cognitive and noncognitive function of individuals with mild cognitive impairment: Study rationale and protocol design.

ABSTRACT:

Introduction

Cognitive training has attracted considerable attention as a safe, economical, and scalable nonpharmacologic intervention in patients with mild cognitive impairment (MCI). However, no study has yet placed sufficient emphasis on the training of executive function. The present study aimed to evaluate whether memory training combined with executive training could lead to improved cognitive and noncognitive performance in patients with MCI. Furthermore, we will explore the neural correlates underlying the changed performances.

Methods

The proposed study is a randomized controlled trial that will include 120 patients with MCI. The eligible patients will be randomized to either an intervention group or a waitlist control group. The intervention group will receive comp

SUBMITTER: Zhang H 

PROVIDER: S-EPMC6205116 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature