Prognostic role of derived neutrophil-to-lymphocyte ratio in surgical triple-negative breast cancer.

ABSTRACT:

Introduction

The role of derived neutrophil-to-lymphocyte ratio (dNLR) in predicting the prognosis of patients with triple-negative breast cancer (TNBC) has not been well studied. Here, we attempted to investigate the significance of dNLR in predicting the prognosis of patients with surgical (nonmetastatic) TNBC.

Methods

A total of 281 patients diagnosed with surgical TNBC in The First Affiliated Hospital of University of Science and Technology of China from February 2005 to March 2015 were retrospectively included in this study. Kaplan-Meier curve analysis was used to assess the disease-free survival (DFS) and overall survival (OS). We used Cox regression model to assess the prognostic significance of pretreatment dNLR and other clinicopathological parameters in TNBC patien

SUBMITTER: Ren K 

PROVIDER: S-EPMC6205537 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature