Evaluation system and web infrastructure for the second cryo-EM model challenge.

ABSTRACT: An evaluation system and a web infrastructure were developed for the second cryo-EM model challenge. The evaluation system includes tools to validate stereo-chemical plausibility of submitted models, check their fit to the corresponding density maps, estimate their overall and per-residue accuracy, and assess their similarity to reference cryo-EM or X-ray structures as well as other models submitted in this challenge. The web infrastructure provides a convenient interface for analyzing models at different levels of detail. It includes interactively sortable tables of evaluation scores for different subsets of models and different sublevels of structure organization, and a suite of visualization tools facilitating model analysis. The results are publicly accessible at http://model-compare.e

SUBMITTER: Kryshtafovych A 

PROVIDER: S-EPMC6205695 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature