Obesity, Weight Loss, and Progression of Disability in Rheumatoid Arthritis.

ABSTRACT:

Objective

Cross-sectional studies have demonstrated that obese patients with rheumatoid arthritis (RA) often report greater disability. The longitudinal effects of obesity, however, are not well-characterized. We evaluated associations between obesity, weight loss, and worsening of disability in patients of 2 large registry studies, which included patients who were followed for longer periods of time.

Methods

This study included patients with RA from the National Data Bank for Rheumatic Diseases (FORWARD) (n = 23,323) and the Veterans Affairs RA (VARA) registry study (n = 1,697). Results of the Health Assessment Questionnaire (HAQ) or Multidimensional HAQ (MD-HAQ) were recorded through follow-up. Significant worsening of disability was defined as an increase of >0.2 in HAQ o

SUBMITTER: Baker JF 

PROVIDER: S-EPMC6205912 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature