Genotypic and Phenotypic Characterization of IncX3 Plasmid Carrying bla _NDM-7 in Escherichia coli Sequence Type 167 Isolated From a Patient With Urinary Tract Infection.

ABSTRACT: Infections due to New Delhi metallo-beta lactamase (NDM)-7-producing Escherichia coli are infrequent and sporadic. In this study, we report one case of recurrent urinary tract infection caused by bla _NDM-7-producing E. coli belonging to phylogenetic group A, sequence type (ST) 167. In this study, we aimed to describe the genotype and phenotype of bla _NDM-7-producing E. coli in China. The isolate exhibited resistance to β-lactam antimicrobials, trimethoprim-sulfamethoxazole, quinolones, and aminoglycosides. bla _NDM-7 is located on a conjugative plasmid designated pJN05NDM-7 belonging to type IncX3. pJN05NDM-7 was fully sequenced and compared with all publicly available bla _NDM-7-harboring plasmids.

SUBMITTER: Hao Y 

PROVIDER: S-EPMC6205962 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature